Summary Pancreatic cancer is a leading cause of cancer-related mortality world-wide. Due to the absence of symptoms in patients with an early-onset pancreatic cancer, it…

Summary Neurofilament, a structural protein released into the blood and CSF by damaged or dead neurons, is increasing in popularity as a biomarker for efficacy…

Summary Developing novel antibiotics to combat the challenge of increasing antibiotic resistance is harder than it seems. Searching for new compounds is limited by scale…

Assembling the Human Genome The human genome project (HGP), a global collaboration involving 20 groups, released the first draft of the human reference genome in…

Inheritance Patterns of Alzheimer’s Disease In spite of its status as a top ten cause of death in the United States, Alzheimer’s Disease (AD) has…

Cancer Vaccines: A Remarkable Step Forward The central goal of the precision medicine field is to treat disease more effectively by taking a personalized approach…

The Immune Landscape of Lung Cancer According to GLOBOCAN, lung cancer is the leading cause of cancer related mortalities world-wide. There are many different types…

What is Sepsis? Sepsis is a life-threatening condition caused by an overreaction of the immune system to an infection, usually bacterial. The extreme immune response…

Summary The viral component of the human gut microbiome is historically understudied, and thus its role in human health is largely unknown. In a recent…

Summary A new DNA sequencing method called CODEC (Concatenating Original Duplex for Error Correction) has been developed by the Broad Institute, which addresses the limitations…

Summary This blog discusses the challenges in understanding and treating multiple myeloma, a type of cancer caused by malignant plasma cells in the bone marrow….

Summary  This Nature study elegantly shows the potential benefits of combining immunotherapy with PI3Kβ inhibitors in treating PTEN-deficient breast cancer and other types of PTEN-deficient…

What are Neoantigen Cancer Vaccines? It may surprise you to know that the immune system is able to recognize and eliminate many cancerous cells from…

Challenges of Tumor Heterogeneity It has long been known to researchers that tumors are like fingerprints: they may share common features, but no two are…

How Do Cells Age? Ask five biologists for a mechanism of cellular aging, and you’ll get five different answers. Numerous cellular processes have been implicated…

Personalized Medicine  The goal of personalized medicine is to optimize patient outcomes by delivering the right treatment to the right patient at the right time….

What are Telomeres? Telomeres are regions of repetitive DNA sequences at the ends of chromosomes that protect the ends of chromosomes from being frayed, degraded…

Advantages and Limitations of Single Cell -Omics The use of single cell genomics has significantly improved our ability to dissect cellular heterogeneity and enabled a…